enzymefunction.org

The Enzyme Function Initiative (EFI) is developing a robust sequence / structure based strategy for facilitating discovery of in vitro enzymatic and in vivo metabolic / physiological functions of unknown enzymes discovered in genome projects. More »

Strategy

 

INTEGRATED STRATEGY

Determining the functions of enzymes discovered through genome sequencing is a major challenge in contemporary biology.  The EFI is using a multi-disciplinary superfamily-based approach for functional assignment that will be applicable to enzymes of all classes.  More »
 

 

 

SEQUENCE
Using bioinformatic analyses, superfamily member sequences (colored circles) are clustered into discrete groups and visualized in sequence similarity networks. Clusters are evaluated for unknown functions to aid selection of targets for the EFI pipeline.  More »

 

STRUCTURE

Structures for targeted enzymes are obtained either by x-ray crystallography or homology modeling.  The structures serve as templates for docking of in silico libraries during virtual screening and enable functional predictions to guide activity screening.  More »

 

REACTION

A variety of in vitro biochemical assays are used to test the computational predictions generated for EFI targets.  Results are used to guide further experiments, such co-crystallization with ligands, and to evaluate the computational methods being developed.  More »

 

FUNCTION

A combination of thorough in vitro analysis and in vivo approaches such as genetic, phenotypic, and metabolomic analysis (as available) cumulates in assigned functions for characterized EFI targets.  Annotations are transferred to receptive public databases.  More »

Announcements

  Signup for our e-mail alert!   |   Download our Newsletters!


New EFI-EST - A web-based sequence similarity network tool from the EFI. More »


New resource - Carbocation numbering system created for isoprenoids. More »


New Metabolite Docker - The Computation Core releases new docking tool.   More »


New Publications - Nine new EFI publications just posted.   More »

EFI Resources / Data Access

Publications

2011 Stourman 04

2011 Publication from Stourman, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011 Stourman 05

2011 Publication from Stourman, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011 Stourman 06

2011 Publication from Stourman, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011 Stourman 07

2011 Publication from Stourman, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011 Stourman 09

2011 Publication from Stourman, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011 Wu sm 02

2011 Publication from Wu, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Wu-sm-03

2011 Publication from Wu, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011 Wu 04

2011 Publication from Wu, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011 Goble 02

2011 Publication from Goble, et al. in ACS Chemical Biology Reprinted with permission. © American Chemical Society

2011 Goble 04

2011 Publication from Goble, et al. in ACS Chemical Biology Reprinted with permission. © American Chemical Society

2011-Huang-03

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Huang-04

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Huang-05

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Huang-06

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Huang-07

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Huang-08

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Huang-09

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Huang-09

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Huang-10

2011 Publication from Huang, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2011-Carlsson-01

2011 Publication from Carlsson, et al. in Nature Chemical Biology Reprinted with permission. © Macmillan Publishers LTD

2011-Carlsson-02

2011 Publication from Carlsson, et al. in Nature Chemical Biology Reprinted with permission. © Macmillan Publishers LTD

2011-Carlsson-03

2011 Publication from Carlsson, et al. in Nature Chemical Biology Reprinted with permission. © Macmillan Publishers LTD

2011-Carlsson-04

2011 Publication from Carlsson, et al. in Nature Chemical Biology Reprinted with permission. © Macmillan Publishers LTD

2011-Schlessinger-01

2011 Publication from Schlessinger, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2011-Schlessinger-02

2011 Publication from Schlessinger, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2011-Schlessinger-03

2011 Publication from Schlessinger, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2011-Schlessinger-04

2011 Publication from Schlessinger, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2011-Gerlt-EFI-03_0.jpg

2011 Publication from Gerlt, et al. in Biochemistry Reprinted with permission. © American Chemical Society.

2011-Gerlt-EFI-04

2011 Publication from Gerlt, et al. in Biochemistry Reprinted with permission. © American Chemical Society.

2011-Gerlt-EFI-05

2011 Publication from Gerlt, et al. in Biochemistry Reprinted with permission. © American Chemical Society.

2011-Gerlt-EFI-06.jpg

2011 Publication from Gerlt, et al. in Biochemistry Reprinted with permission. © American Chemical Society.

2011-Gerlt-EFI-07

2011 Publication from Gerlt, et al. in Biochemistry Reprinted with permission. © American Chemical Society.

2011-Fan-02.jpg

2011 Publication from Fan, et al. in Journal of Chemical Information and Modeling Reprinted with permission. © American Chemical Society.

2011-Fan-03.jpg

2011 Publication from Fan, et al. in Journal of Chemical Information and Modeling Reprinted with permission. © American Chemical Society.

2011-Fan-04

2011 Publication from Fan, et al. in Journal of Chemical Information and Modeling Reprinted with permission. © American Chemical Society.

2011-Fan-05

2011 Publication from Fan, et al. in Journal of Chemical Information and Modeling Reprinted with permission. © American Chemical Society.

2011-Fan-06

2011 Publication from Fan, et al. in Journal of Chemical Information and Modeling Reprinted with permission. © American Chemical Society.

2011-Fan-07

2011 Publication from Fan, et al. in Journal of Chemical Information and Modeling Reprinted with permission. © American Chemical Society.

2011-Fan-02.jpg

2011 Publication from Fan, et al. in Journal of Chemical Information and Modeling Reprinted with permission. © American Chemical Society.

2011-Gerlt-Divergent-01

2011 Publication from Gerlt, et al. in Journal of Biological Chemistry Reprinted with permission. © American Society for Biochemistry and Molecular Biology

2011-Gerlt-Divergent-02

2011 Publication from Gerlt, et al. in Journal of Biological Chemistry Reprinted with permission. © American Society for Biochemistry and Molecular Biology

2011-Gerlt-Divergent-03

2011 Publication from Gerlt, et al. in Journal of Biological Chemistry Reprinted with permission. © American Society for Biochemistry and Molecular Biology

2011-Gerlt-Divergent-04

2011 Publication from Gerlt, et al. in Journal of Biological Chemistry Reprinted with permission. © American Society for Biochemistry and Molecular Biology

2011-Brown-02.jpg

2011 Publication from Brown, et al. in Journal of Biological Chemistry Reprinted with permission. © American Society for Biochemistry and Molecular Biology

2011-Brown

2011 Publication from Brown, et al. in Journal of Biological Chemistry Reprinted with permission. © American Society for Biochemistry and Molecular Biology

2011-Brown-03

2011 Publication from Brown, et al. in Journal of Biological Chemistry Reprinted with permission. © American Society for Biochemistry and Molecular Biology

2011-Brown-04.jpg

2011 Publication from Brown, et al. in Journal of Biological Chemistry Reprinted with permission. © American Society for Biochemistry and Molecular Biology

2011-Kamat-01.jpg

2011 Publication from Kamat, et al. in Nature Reprinted with permission. © Macmillan Publishers LTD

2011-Kamat-02.jpg

2011 Publication from Kamat, et al. in Nature Reprinted with permission. © Macmillan Publishers LTD

2011-Kamat-03.jpg

2011 Publication from Kamat, et al. in Nature Reprinted with permission. © Macmillan Publishers LTD

2011-Kamat-04.jpg

2011 Publication from Kamat, et al. in Nature Reprinted with permission. © Macmillan Publishers LTD

Wallrapp-01

2013 Publication from Wallrapp, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Wallrapp 02

2013 Publication from Wallrapp, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Wallrapp 03

2013 Publication from Wallrapp, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 wallrapp 04

2013 Publication from Wallrapp, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 wallrapp 05

2013 Publication from Wallrapp, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Wallrapp 06

2013 Publication from Wallrapp, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Ghodge

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 02

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 03

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 04

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Godge

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 06

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 07

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 08

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 08

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 09

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 10

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 11

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Ghodge 13

2013 Publication from Ghodge, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Almo 01

2013 Publication from Almo, et al. in Current Opinion in Structural Biology 23 Reprinted with permission. © Elsevier

2013 Almo 02

2013 Publication from Almo, et al. in Current Opinion in Structural Biology 23 Reprinted with permission. © Elsevier

2013 Almo 03

2013 Publication from Almo, et al. in Current Opinion in Structural Biology 23 Reprinted with permission. © Elsevier

2013 Almo 04

2013 Publication from Almo, et al. in Current Opinion in Structural Biology 23 Reprinted with permission. © Elsevier

2013 Daughtry 01

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Daughtry 02

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Daughtry 03

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Daughtry 04

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Daughtry 05

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Daughtry 06

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Daughtry 07

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Daughtry 08

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Daughtry 09

2013 Publication from Daughtry, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 01

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 02

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 03

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 04

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 05

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 06

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 07

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 08

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pan 09

2013 Publication from Pan, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Pandya 01

2011 Publication from Schlessinger, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Pandya 01

2013 Publication from Pandya, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Pandya 02

2013 Publication from Pandya, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Pandya 03

2013 Publication from Pandya, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Pandya 04

2013 Publication from Pandya, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Pandya 05

2013 Publication from Pandya, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Pandya 06

2013 Publication from Pandya, et al. in Proc Natl Acad Sci USA Reprinted with permission. © National Academy of Sciences, USA

2013 Tian 01

2013 Publication from Tian, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Tian 02

2013 Publication from Tian, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Tian 03

2013 Publication from Tian, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Tian 04

2013 Publication from Tian, et al. in Biochemistry Reprinted with permission. © American Chemical Society

2013 Hitchcock 01

2013 Publication from Hitchcock, et al. in Journal of the American Chemical Society. Reprinted with permission. © American Chemical Society

2013 Hitchcock 02

2013 Publication from Hitchcock, et al. in Journal of the American Chemical Society. Reprinted with permission. © American Chemical Society

2013 Hitchcock 03

2013 Publication from Hitchcock, et al. in Journal of the American Chemical Society. Reprinted with permission. © American Chemical Society

2013 Hitchcock 04

2013 Publication from Hitchcock, et al. in Journal of the American Chemical Society. Reprinted with permission. © American Chemical Society

2013 Hitchcock 05

2013 Publication from Hitchcock, et al. in Journal of the American Chemical Society. Reprinted with permission. © American Chemical Society

2013 Hitchcock 06

2013 Publication from Hitchcock, et al. in Journal of the American Chemical Society. Reprinted with permission. © American Chemical Society

2013 Bryan 01

2013 Publication from Bryan, et al. Reprinted with permission. © International Union Crystallographyy

2013 Bryan 02

2013 Publication from Bryan, et al. Reprinted with permission. © International Union Crystallographyy

2013 Bryan 03

2013 Publication from Bryan, et al. Reprinted with permission. © International Union Crystallographyy

2013 Bryan 04

2013 Publication from Bryan, et al. Reprinted with permission. © International Union Crystallographyy

2013 Zhao 01

2013 Publication from Zhao, et al. Reprinted with permission. Copyright © Nature Publishing Group

2013 Zhao 02

2013 Publication from Zhao, et al. Reprinted with permission. Copyright © Nature Publishing Group

2013 Zhao 03

2013 Publication from Zhao, et al. Reprinted with permission. Copyright © Nature Publishing Group

2013 Zhao 04

2013 Publication from Zhao, et al. Reprinted with permission. Copyright © Nature Publishing Group

2013 Dong 01

2013 Publication from Dong, et al. Reprinted with permission Oxford University Press. Copyright © Bioinformatics

2013 Dong 02

2013 Publication from Dong, et al. Reprinted with permission Oxford University Press. Copyright © Bioinformatics

2013 Dong 03

2013 Publication from Dong, et al. Reprinted with permission Oxford University Press. Copyright © Bioinformatics

2013 Dong 04

2013 Publication from Dong, et al. Reprinted with permission Oxford University Press. Copyright © Bioinformatics

2013 Dong 05

2013 Publication from Dong, et al. Reprinted with permission Oxford University Press. Copyright © Bioinformatics

2013 Dong 06

2013 Publication from Dong, et al. Reprinted with permission Oxford University Press. Copyright © Bioinformatics

2013 Goble 01

2013 Publication from Goble, et al. Reprinted with permission. Copyright © American Chemical Society

2013 Goble 02

2013 Publication from Goble, et al. Reprinted with permission. Copyright © American Chemical Society

2013 Goble 03

2013 Publication from Goble, et al. Reprinted with permission. Copyright © American Chemical Society

2013 Goble 04

2013 Publication from Goble, et al. Reprinted with permission. Copyright © American Chemical Society

2013 Goble 05

2013 Publication from Goble, et al. Reprinted with permission. Copyright © American Chemical Society

2013 Goble 06

2013 Publication from Goble, et al. Reprinted with permission. Copyright © American Chemical Society

Structures

PDB Deposition 3TJ4 by Vetting et al
New structure for EFI target 502087 from the Enolase superfamily.

PDB Deposition 2YB1 by Vetting et al
New structure for EFI target 500202 from the Amidohydrolase superfamily.

PDB Deposition 2YB4 by Vetting et al
New structure for EFI target 500202 from the Amidohydrolase superfamily.

PDB Deposition 2YBD by Vetting et al
New structure for EFI target 900338 from Haloacid dehalogenases superfamily.

PDB Deposition 3QU2 by Patskovsky et al
New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QU4 by Patskovsky et al
New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QU5 by Patskovsky et al
New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QU7 by Patskovsky et al
New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QU9 by Patskovsky et al
New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QUB by Patskovsky et al
New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QUC by Patskovsky et al

New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QUQ by Patskovsky et al

New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QUT by Patskovsky et al

New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QX7 by Patskovsky et al

New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QXG by Patskovsky et al

New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3QYP by Patskovsky et al

New structure for EFI target 900250 from Haloacid dehalogenases superfamily.

PDB Deposition 3R09 by Vetting et al
New structure for EFI target 900338 from the Haloacid dehalogenases superfamily.

PDB Deposition 3RCM by Kim et al
New structure for EFI target 500140 from the Amidohydrolase superfamily.

PDB Deposition 3RHG by Patskovsky et al
New structure for EFI target 500319 from the Amidohydrolase superfamily.

PDB Deposition 3RR1 by Patskovsky et al
New structure for EFI target 500653 from the Enolase superfamily.

PDB Deposition 3RRA by Patskovsky et al
New structure for EFI target 500653 from the Enolase superfamily.

PDB Deposition 354T by Ramagopal et al
New structure for EFI target 500288 from the Amidohydrolase superfamily.

PDB Deposition 3SJN by Patskovsky et al
New structure for EFI target 500646 from the Enolase superfamily.

PDB Deposition 3T6C by Vetting et al
New structure for EFI target 501676 from the Enolase superfamily.

PDB Deposition 3THU by Vetting et al
New structure for EFI target 501683 from the Enolase superfamily.

PDB Deposition 3TJI by Vetting et al
New structure for EFI target 501662 from the Enolase superfamily.

PDB Deposition 3TOT by Patskovsky et al
New structure for EFI target 501058 from the Glutathione transferases superfamily.

PDB Deposition 3TOU by Patskovsky et al
New structure for EFI target 501058 from the Glutathione transferases superfamily.

PDB Deposition 3TOY by Patskovsky et al
New structure for EFI target 501651 from the Enolases superfamily.

PDB Deposition 3TS7 by Patskovsky et al
New structure for EFI target 501961 from the Isoprenoid synthases Type I superfamily.

PDB Deposition 3TTE by Patskovsky et al
New structure for EFI target 501651 from the Enolase superfamily.

PDB Deposition 3TW9 by Patskovsky et al
New structure for EFI target 501679 from the Enolases superfamily.

PDB Deposition 3TWA by Patskovsky et al
New structure for EFI target 501679 from the Enolases superfamily.

PDB Deposition 3TWB by Patskovsky et al
New structure for EFI target 501679 from the Enolases superfamily.

PDB Deposition 3UAP by Patskovsky et al
New structure for EFI target 501774 from the Glutathione transferases superfamily.

PDB Deposition 3UAR by Patskovsky et al
New structure for EFI target 501774 from the Glutathione transferases superfamily.

PDB Deposition 3UBK by Patskovsky et al
New structure for EFI target 501770 from the Glutathione transferases superfamily.

PDB Deposition 3UBL by Patskovsky et al
New structure for EFI target 501770 from the Glutathione transferases superfamily.

PDB Deposition 3UCA by Patskovsky et al
New structure for EFI target 501974 from the Isoprenoid synthases Type I superfamily.

PDB Deposition 3UF0 by Vetting et al
New structure for EFI target 502044 from the Enolase superfamily.

PDB Deposition 3UGV by Vetting et al
New structure for EFI target 501650 from the Enolase superfamily.

PDB Deposition 3UJ2 by Vetting et al
New structure for EFI target 502054 from the Enolase superfamily.

PDB Deposition 3V3W by Vetting et al
New structure for EFI target 502161 from the Enolase superfamily.

PDB Deposition 3V4B by Vetting et al
New structure for EFI target 502161 from the Enolase superfamily.

PDB Deposition 3V7P by Patskovsky et al
New structure for EFI target 500396 from the Amidohydrolase superfamily.

PDB Deposition 3VA8 by Patskovsky et al
New structure for EFI target 502278 from the Enolase superfamily.

PDB Deposition 3VC5 by Patskovsky et al
New structure for EFI target 502310 from the Enolase superfamily.

PDB Deposition 3VC6 by Patskovsky et al
New structure for EFI target 502310 from the Enolase superfamily.

PDB Deposition 3VCN by Patskovsky et al
New structure for EFI target 502209 from the Enolase superfamily.

PDB Deposition 3VDG by Patskovsky et al
New structure for EFI target 502282 from the Enolase superfamily.

PDB Deposition 3VFC by Patskovsky et al
New structure for EFI target 502282 from the Enolase superfamily.

PDB Deposition 4DCC by Patskovsky et al
New structure for EFI target 501088 from the Haloacid dehalogenases superfamily.

PDB Deposition 3DEJ by Patskovsky et al
New structure for EFI target 501089 from the Glutathione transferases superfamily.

PDB Deposition 4DFD by Patskovsky et al
New structure for EFI target 501088 from the Haloacid dehalogenases superfamily.

PDB Deposition 4DHD by Patskovsky et al
New structure for EFI target 501992 from the Isoprenoid synthases Type I
superfamily.

4DLF

PDB Deposition 4DLF by Vetting et al
New structure for EFI target 500235 from the Amidohydrolase superfamily.

PDB Deposition 4DLM by Vetting et al
New structure for EFI target 500235 from the Amidohydrolase superfamily.

PDB Deposition 4DN1 by Enolase et al
New structure for EFI target 502088 from the Enolase superfamily.

PDB Deposition 4DNM by Vetting et al
New structure for EFI target 500235 from the Amidohydrolase superfamily.

PDB Deposition 4DO7 by Vetting et al
New structure for EFI target 500235 from the Amidohydrolase superfamily.

PDB Deposition 4DW8 by Vetting et al
New structure for EFI target 900331 from the Haloacid dehalogenases superfamily.

PDB Deposition 4DWO by Vetting et al
New structure for EFI target 900331 from the Haloacid dehalogenases superfamily.

PDB Deposition 4DX3 by Vetting et al
New structure for EFI target 502086 from the Enolase superfamily.

PDB Deposition 4DXK by Vetting et al
New structure for EFI target 502086 from the Enolase superfamily.

4dye
PDB Deposition 4dye by Vetting et al
New structure for EFI target 502095 from Enolase superfamily.

4dzi
PDB Deposition 4DZI by Patskovsky et al
New structure for EFI target 500390 from Amidohydrolase superfamily.

4hpn
PDB Deposition 4hpn by Vetting et al
New structure for EFI target 500704 from Enolases superfamily. 

4GGB

PDB Deposition 4GGB by Vetting et al
New structure for EFI target 500704 from Enolase superfamily.

PDB Deposition 4GF0 by Glenn et al
New structure for EFI target 501084 from Glutathione transferases superfamily.

PDB Deposition 4G9B by Vetting et al
New structure for EFI target 501172 from Haloacid dehalogenases superfamily.

4EEN

PDB Deposition 4EEN by Patskovsky et al

New structure for EFI target 501256 from Haloacid dehalogenases superfamily.

4EEL

PDB Deposition 4EEL by Patskovsky et al

New structure for EFI target 501256 from Haloacid dehalogenases superfamily.

4EEK

PDB Deposition 4EEK by Patskovsky et al

New structure for EFI target 501256 from Haloacid dehalogenases superfamily.

PDB Deposition 4EZE by Patskovsky et al

New structure for EFI target 501419 from Haloacid dehalogenases superfamily.

4GIS

PDB Deposition 4GIS by Vetting et al

New structure for EFI target 501692 from Enolases superfamily.

4GGH

PDB Deposition 4GGH by Vetting et al

New structure for EFI target 501692 from Enolases superfamily.

PDB Deposition 4GIR by Vetting et al

New structure for EFI target 501962 from Enolases superfamily.

4EXJ

PDB Deposition 4EXJ by Patskovsky et al

New structure for EFI target 501752 from Glutathione transferases superfamily.

4HOJ

PDB Deposition 4HOJ by Vetting et al

New structure for EFI target 501841 from Glutathione transferases superfamily.

4ECJ

PDB Deposition 4ECJ by Patskovsky et al

New structure for EFI target 501853 from Glutathione transferases superfamily.

4ECI

PDB Deposition 4ECI by Patskovsky et al

New structure for EFI target 501853 from Glutathione transferases superfamily.

PDB Deposition 4GCI by Vetting et al

New structure for EFI target 501894 from Glutathione transferases superfamily.

4G9H

PDB Deposition 4G9H by Vetting et al

New structure for EFI target 501894 from Glutathione transferases superfamily.

4F62

PDB Deposition 4F62 by Vetting et al

New structure for EFI target 900250 from Isoprenoid synthases Type I superfamily.

4Fp4

PDB Deposition 4FP4 by Patskovsky et al

New structure for EFI target 501993 from Isoprenoid synthases Type I superfamily.

4H2H

PDB Deposition 4H2H by Vetting et al

New structure for EFI target 502101 from Enolases superfamily.

4H1Z

PDB Deposition 4H1Z by Patskovsky et al

New structure for EFI target 502101 from Enolases superfamily.

4F4R

PDB Deposition 4F4R by Patskovsky et al

New structure for EFI target 502114 from Enolases superfamily.

4H83

PDB Deposition 4H83 by Kim et al

New structure for EFI target 502127 from Enolases superfamily.

4EUM

PDB Deposition 4EUM by Vetting et al

New structure for EFI target 502132 from Haloacid dehalogenases superfamily.

4EBU

PDB Deposition 4EBU by Vetting et al

New structure for EFI target 502132 from Enolase superfamily.

4E69

PDB Deposition 4E69 by Vetting et al

New structure for EFI target 502132 from Enolases superfamily.

4EUN

PDB Deposition 4EUN by Vetting et al

New structure for EFI target 502144 from Enolases superfamily.

4GM

PDB Deposition 4GM6 by Patskovsky et al

New structure for EFI target 502146 from Enolases superfamily.

4e38

PDB Deposition 4E38 by Patskovsky et al

New structure for EFI target 502156 from Enolases superfamily.

4FI4

PDB Deposition 4FI4 by Patskovsky et al

New structure for EFI target 502214 from Enolase superfamily.

4E4F

PDB Deposition 4E4F by Patskovsky et al

New structure for EFI target 502240 from Enolases superfamily.

4G8T

PDB Deposition 4G8T by Vetting et al

New structure for EFI target 502313 from Enolases superfamily.

4GFI

PDB Deposition 4GFI by Vetting et al

New structure for EFI target 502318 from Enolases superfamily.

4GXW

PDB Deposition 4GXW by Vetting et al

New structure for EFI target 505188 from Amidohydrolase superfamily.

4GIT

PDB Deposition 4GLT by Patskovsky et al

New structure for EFI target 507160 from Glutathione transferases superfamily.